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Cancer Clinical Trials: A Critical Appraisal (Paperback)

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137.87 $

168.43 $

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Beskrivelse

The book is devoted to improved communication between clinicians, psychologists, and legal experts on the one hand and methodologists on the other. Mathematical formalism is therefore kept to a minimum and on a level acceptable to all sides. The contributions provide strictly organized coverage of the following topics: scientific fundamentals; heterogeneous treatment effects; combined information in historical controls, overviews, and comprehensive cohort studies; subjective opinions and informed consent; and assessment of quality of life. It is these aspects that are crucial in the planning of clinical trials and in the analysis and interpretation of results. Since there is still much debate between clinicians and statisticians on the subject, this book may prevent the reader from embarking on poorly planned clinical trials.

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